H. M.’s Medial Temporal Lobe Lesion: Findings from Magnetic Resonance Imaging
نویسندگان
چکیده
منابع مشابه
H. M.'s medial temporal lobe lesion: findings from magnetic resonance imaging.
Although neuropsychological studies of the amnesic patient H. M. provide compelling evidence that normal memory function depends on the medial temporal lobe, the full extent of his surgical resection has not been elucidated. We conducted magnetic resonance imaging studies to specify precisely the extent of his bilateral resection and to document any other brain abnormalities. The MRI studies in...
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BACKGROUND Proton magnetic resonance spectroscopy (MRS) of the hippocampus is useful in lateralising the epileptic focus in temporal lobe epilepsy for subsequent surgical resection. Previous studies have reported abnormal contralateral MRS values in up to 50% of the patients. OBJECTIVE To identify the contributing factors to contralateral damage, as determined by MRS, and its extension in pat...
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There is great interest in the cognitive consequences of hippocampal volume loss in developmental amnesia (DA). In many DA cases, volume loss occurs before the hippocampus is fully developed, and yet little is known about the locus, extent, and distribution of damage in these cases. We used high-resolution MRI to manually segment the medial temporal lobe (MTL) subregions in H.C., an adult with ...
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The paper by Wahlund et al in this issue (pp 630–635) tries to shed light on the usefulness of biological markers in the routine diagnosis of Alzheimer’s disease. Tissue loss in the medial temporal lobe regions as detected by MRI is one of the most feasible and accurate markers developed to date and investigating its usefulness in a clinical setting is potentially relevant. The paper has two ma...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1997
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.17-10-03964.1997